So what’re the differences between CBD, CBDA, CBGA and marijuana plants you’d buy at a dispensary? CBD and CBG plus their acidic forms CBDA and CBGA When we think of cannabinoids, we commonly think of neutral forms like CBD and CBG . However, lately, there is some scientific data available There's new research that's come out about CBGA. Come on by the store, call or email for more information about our Quality CBGA Products!
Cannabis and COVID: Key differences between CBD, CBDA and CBGA
New study finds cannabis compounds block coronavirus proteins
Ken Haddad , Digital Content Manager
GRANTHAM, ENGLAND – AUGUST 27: Hemp oil is tested for quality in the process department at British CBD oil producer Crop England on August 27, 2021 in Grantham, England. British CBD oil was founded in 2019 by Mike and Jackie Lamyman. The popularity of CBD oil from the cannabis family of plants has grown in recent years due to its health properties. (Chris Furlong, 2021 Getty Images)
A study published this week by researchers at Oregon State University found some hemp compounds have the ability to prevent the virus that causes COVID-19 from entering human cells.
Findings of the study led by Richard van Breemen, a researcher with Oregon State’s Global Hemp Innovation Center, College of Pharmacy and Linus Pauling Institute, were published this week in the Journal of Natural Products.
Hemp, known scientifically as cannabis sativa, is a source of fiber, food and animal feed, and multiple hemp extracts and compounds are added to cosmetics, body lotions, dietary supplements and food, van Breemen said.
“We identified several cannabinoid ligands and ranked them by affinity to the spike protein,” van Breemen said. “The two cannabinoids with the highest affinities for the spike protein were CBDA and CBGA, and they were confirmed to block infection.”
So what’re the differences between CBD, CBDA, CBGA and marijuana plants you’d buy at a dispensary?
CBD, an abbreviation for cannabidiol, doesn’t produce any psychoactive effects. It’s likely what you see at some pharmacies, health stores or dispensaries.
It’s a very versatile compound, which makes it ideal for oils, gummies, lotions, creams and other products. Hemp contains a lot of CBD.
But CBD is not the compound that was tested in the Oregon State study. CBD is activated in hemp plants from its original form — CBDA.
CBDA, known as cannabidiolic acid, is secreted in the stems, leaves and flowers of a cannabis plant. When the plant undergoes activation (a process with heat), the acid is removed from the CBDA, activating CBD.
They have similar compounds, but CBDA is not as versatile. It’s usually extracted by “juicing” plant material, and can be added to foods, drinks, or used in tinctures, concentrated herbal extracts.
But basically, CBDA is the raw form of CBD. And it’s not as easy to find. But you can buy it. (It has not been studied as much as CBD)
CBGA, known as cannabigerolic acid, is considered the “mother cannabinoid,” because without it, there is no CBD, CBDA or THC.
CBGA compounds are similar to other cannabinoids, but it hasn’t been studied nearly as much as the others. It’s non-intoxicating. Enzymes called synthases are responsible for converting the CBGA into molecules such as THCA, the raw, unactivated molecule that converts to THC after heat is applied.
Again, you can find this in oils and tinctures online, but it’s harder to find and at times, pretty expensive, because it’s harder to extract.
What about smoking marijuana?
At this point, it doesn’t appear that just smoking marijuana, even a heavy CBD strain, will produce the effects reported in this study. We don’t have enough information to suggest it.
CBDA or CBGA products, like oils, offering these in their raw form, do not work the same in marijuana products, which usually include high levels of THC, the psychoactive compound that makes you high.
And before trying something new, do your research, talk to your doctor and make sure it’s something you should bring into your life. Check out Project CBD for some information on getting started.
Copyright 2022 by WDIV ClickOnDetroit – All rights reserved.
About the Author:
Ken Haddad is the digital content and audience manager for WDIV / ClickOnDetroit.com. He also authors the Morning Report Newsletter and various other newsletters. He’s been with WDIV since 2013. He enjoys suffering through Lions games on Sundays in the fall.
CBD and CBG plus their acidic forms CBDA and CBGA
When we think of cannabinoids, we commonly think of neutral forms like CBD and CBG. However, lately, there is some scientific data available also on acidic forms, which are shown to have several positive impacts on the human body. Did you already hear about CBGA and CBDA?
Biosynthesis of cannabinoids
In fresh hemp, we can mostly find acidic forms of cannabinoids. Acidic forms are precursors of neutral forms, which means that neutral forms are formed from acidic forms. This process is called oxidation and occurs naturally. It can be fastened up by exposing hemp to heat and/or light.
CBGA is also known as the “mother molecule,” and all other cannabinoids are formed out of it. CBDA is synthesized from CBGA by an enzyme CBDA synthase. CBDA can further oxidize. When the process of oxidation happens, we get CBD. But not all CBGA is converted to other cannabinoids by enzymes. Sometimes oxidation process occurs to CBGA as well. In this case, we get CBG.
Potential benefits of CBDA and CBGA
We are all familiar with the benefits of the most famous cannabinoid – CBD. It is helpful to know that acidic forms of cannabinoids, like CBDA and CBGA, provide certain pharmacological activities that we can benefit from.
CBDA is supposed to have anti-inflammatory, anti-emetic, and anti-anxiety properties (Rock, 2015; Rock, 2020). Therefore, it could help reduce inflammations in our bodies, help us ease or prevent the feeling of nausea and help us cope with stress-related symptoms.
CBGA, on the other hand, is supposed to be a novel cannabinoid in the therapy of childhood epilepsy (Anderson, 2021). It is also known to have neuroprotective properties and could be a potential remedy for fighting Alzheimer’s disease (Burgaz, 2021).
Most recent discoveries
In a recently published study by van Breemen et al. (2022), CBGA and CBDA were shown to block cellular entry of the SARS-CoV-2 virus and its variants. By preventing infection of human cells by SARS-CoV-2 and preventing the entry of SARS-CoV-2 into cells, CBGA and CBDA have the potential to prevent as well as treat infection by SARS-CoV-2.
We are all hoping to get our pre-covid lives back. We suggest you give a combination of CBGA and CBDA a chance and try to protect yourself and your loved ones from the virus.
Oregon Hemp House CBGA+CBG Oil 1000mg/30ML made of organic MCT oil
THE Very first CBGA oil we ever carried! Oregon Hemp House EXCLUSIVE Proprietary Formula This super cannabinoid has been shown to affect different functions that are regulated by the endocannabinoid system. There’s new research that’s come out about CBGA. Come on by the store, call or email for more information about our Quality CBGA Products!
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Oregon Hemp House CBGA+CBG Oil 1000mg/30ML is made of organic MCT oil, CBGA hemp concentrate.
We are excited to bring CBGA to Oregon Hemp House. It is the first CBGA oil we have ever carried! Why is this exciting? There is new research that has come out about CBGA. We already knew it was the “mother of all cannabinoids” because it’s a precursor for more of the other cannabinoids like CBG, CBD, CBC, THC (Oregon Hemp House CBGA/CBG oil is hemp-derived and below 0.3% THC which means no psychoactive effects). We provide a Certificate Of Analysis COA which provides data about the testing lab, the brand and product question, along with the potency of the ingredients the product contains. Our products surpass quality assurance levels in every batch and individual bottles.
This super cannabinoid has been shown to affect different functions that are regulated by the endocannabinoid system. Come on by the store, call or email for more information about CBGA!
Here’s a link to an article about a new OSU research on hemp compounds that show the ability to prevent the virus that causes Covid-19 from entering human cells by the local KVAL-13 about CBGA.
We look forward to new products and studies with CBGA!
Contains less than 0.3% THC, non-psychoactive
Directions: Shake bottle. Take one serving (1ML) under tongue and hold for 30 seconds before swallowing.